Bioanalytical Associate- Wilmington, Delaware

This role will focus on supporting in-vitro ADME (Absorption, Distribution, Metabolism, and Excretion) studies and plasma sample analysis in preclinical drug development. The successful candidate will play a pivotal role in the analysis and interpretation of bioanalytical data to support early-stage drug discovery.

Key Responsibilities:

• Support ADME Studies: Conduct routine ADME assays, such as protein binding and metabolic stability, to generate key data supporting drug development decisions.
• Plasma Sample Analysis: Prepare and analyze plasma samples for pharmacokinetic studies, including the measurement of drug concentration, metabolite profiling, and related biomarkers.
• Data Interpretation & Reporting: Analyze data sets, provide scientific interpretation, and communicate results to cross-functional teams in a clear and concise manner.
• Record-Keeping: Maintain concise and accurate records of all study activities in accordance with industry guidelines and company policies.
• Troubleshooting and Continuous Improvement: Troubleshoot assay issues, propose corrective actions, and implement process improvements to enhance the efficiency and reliability of bioanalytical data.

Qualifications:

• Bachelor’s degree in Analytical Chemistry, Biochemistry, or a related field.
• 1+ years of hands-on lab experience in bioanalysis, with a focus on ADME/PK studies and plasma sample analysis.

Technical Expertise:

Hands-on lab experience with ADME screening assays, such as protein binding and microsomal stability. Experience with plasma sample bioanalysis in support of non-clinical pharmacokinetic studies. Experience with LC-MS/MS, HPLC, UPLC, and related analytical techniques for the quantification and characterization of drug candidates in biological samples is a plus. Strong analytical and troubleshooting skills with the ability to interpret complex datasets.

Preferred Qualifications:

• Familiarity with drug discovery and development, especially within preclinical research.
• Experience with quantitative LC-MS/MS bioanalytical techniques and ABSciex mass spectrometers. Knowledge of relevant bioanalytical software (e.g., Analyst, Prism) is a plus.