Baptist Memorial Hospital - North Mississippi, founded in 1912, is a 217-bed acute care hospital that serves the northern third of the state. Its newly built facility at 1100 Belk Boulevard was just completed.

A designated Baby-Friendly hospital that offers breastfeeding counseling and a unique program for expectant mothers called Beautiful Beginnings, North Mississippi also received a Leapfrog Hospital Safety Grade of 'A' in 2020.