Position Summary:

• Perform research and testing within a CLIA-certified, high-complexity clinical testing and R&D laboratory.

Essential Duties and Responsibilities:

• Assist in the development, validation, and implementation of cell pathway and signaling assays for human cells from various tissue sources and cell lines.
• Culture and prepare consistent batches of human cells for assays.
• Maintain multiple human cell samples grown under various laboratory conditions.
• Perform assays to identify and sort cell types by biomarkers.
• Conduct genotypic and pathway characterizations for human cells.
• Collaborate with science directors to develop new assays or troubleshoot existing assays.
• Manage, organize, and maintain laboratory resources, instruments, procedures, and protocols.
• Provide documentation control support, including cell assay R&D result records and procedures.
• Acquire competency in several clinical diagnostic procedures.
• Adhere to and facilitate the laboratory's quality control policies.
• Document all quality control activities, instrument calibrations, and maintenance.
• Follow laboratory's established policies and procedures when test systems do not meet acceptable performance levels.
• Identify opportunities to reduce assay variance and prevent equipment downtime.
• Document corrective actions when test systems deviate from performance specifications.
• Report to work as scheduled and maintain compliance with HIPAA requirements.
• Follow laboratory standard operating procedures and CAP/CLIA regulations.
• Adhere to safety regulations.

Qualifications:

• Demonstrated ability to carry out human cell experiments independently.
• Practical knowledge of human cell culture for performing live cell assays.
• Advanced degree or equivalent experience in Cell Biology, Oncology, or Translational/Systems Medicine, with experience in molecular cell biology, human cell culture, and live cell assay development.
• Ph.D. with experience developing activity-based live cell assays for small molecules, or
• Master’s Degree with 5+ years of industry experience in developing activity-based live cell assays, or
• Bachelor’s Degree with 8+ years of industry experience in developing activity-based live cell assays.
• Experience in a medical laboratory or biotechnology setting aligned with job responsibilities.
• Experience developing assays using techniques such as:
• qPCR, flow cytometry, automated western blot, RNA-seq, plate-based fluorescent/luminescent,
• Impedance-based assays, metabolic profiling, oxygen consumption, imaging.
• Strong organizational skills for managing lab functions, documentation, and complex processes.
• Experience in quality control, preventative maintenance, and SOPs to ensure consistent high-quality data.
• Excellent verbal and written communication skills.

Capabilities:

• Analytical: Collect and analyze data, perform reagent concentration calculations.
• Demonstrate attention to detail and knowledge of basic statistical principles.
• Design: Design basic workflows and procedures under supervision.