Who We Are:

At BioHybrid Solutions, our goal is to make novel and powerful medicines to save lives.

Our core technology, called NanoArmor®, has spun out of Carnegie Mellon University. This technology allows for precision growth of polymers from proteins through biologically compatible Atom Transfer Radical Polymerization (ATRP).

Our lead program, a nanoarmored enzyme, is advancing toward IND. At the same time, we have launched the development of a pipeline of antibody-drug conjugates (ADCs) for Oncology. 

Our ADCs are exciting. Compared to the state of the art where 8 small molecule payloads are attached to an antibody, we can design ultra-high DAR ADCs. This opens many new opportunities to explore novel antibodies and payloads and sets us apart from the crowd.

This is a great time to join an exciting and growing team and play a meaningful role in our goal to save lives. We look forward to meeting you!

What you’ll be doing

As a Scientist in the Biology department, you will independently conduct studies and apply findings to support development of candidate molecules.  You will contribute to collaborative projects by designing and executing a range of molecular, cellular and associated analytic experiments, as well as interpreting results to advance the team's scientific objectives and the company's research goals.

The ideal candidate will have a solid foundation in molecular biology, biochemistry, or a related field, combined with a passion for continuous learning and professional growth within our organization experience.

Key Responsibilities:

·       Develop and execute cell and molecular biology protocols, adhering to established guidelines and striving for process improvements.

·       Participate in the development and optimization of new methods and techniques

·       Utilize software and statistical tools to interpret, analyze, and present experimental data, ensuring high levels of accuracy and reliability.

·       Maintain meticulous records of experimental protocols, data, and findings in laboratory notebooks and databases.

·       Review scientific publications and keep abreast of emerging methodologies to inform and enhance the development and refinement of experimental protocols in the field.

·       Lead project meetings and scientific discussions, providing insights and updates on research progress.

·       Interpret research findings and identify next steps for further study or product improvement.

·       Develop and maintains productive relationships with colleagues both within the protein department and across different functional teams to enhance collaborative problem-solving and project advancement.

·       Ensure adherence to regulatory standards by authoring, updating, and assisting in the maintenance of Standard Operating Procedures (SOPs) and quality protocols.

·       Contribute to maintaining the cleanliness and order of the lab, while promptly notifying the appropriate person of any equipment-related concerns.

·       Understand, follow, and embrace laboratory safety policies to ensure compliance with company safety requirements and regulatory guidelines.

·       Execute other duties and responsibilities as assigned, demonstrating flexibility and commitment to the organization’s goals.

Qualifications

·       Preferred Education:  PhD degree in Biochemistry, Molecular Biology, Cancer Biology, or a related scientific discipline

·       Experience:  A minimum of 5 years of hands-on lab experience. 

·       Proficiency with relevant cell biology, molecular biology and microscopy techniques.

·       Experience with mouse models of cancer and comfort working with biological samples.

·       Solid communication (written and verbal) skills with the ability to translate information into a meaningful, understandable context and message, regardless of the format (e.g., documents, public speaking, virtual presentations.)

·       Demonstrated proficiency to apply learned techniques and contribute to analysis and investigation to solve problems.

·       Ability to serve as subject matter expert on key techniques to serve as a leader, trainer, and mentor for other team members. 

·       Demonstrated ability to work with a high degree of creativity and autonomy, including proficient multitasking skills within a preclinical development environment. 

·       Ability to develop and maintain professional, trusting, positive working relationships with all employees in thecompany.

·       Knowledge of occupational safety and health rules and regulations.

·       High ethical and confidentiality standards.

·       Strong computer skills and proficient in Microsoft Office applications.

Job Specifics

·       Permanent full-time employee.

·       Work Schedule:  Monday through Friday. Must be available to work during BHS “core working hours” of 10:00 am ET and 3:00 pm ET. Flexible schedule outside of those hours.

·       Special Considerations:  Working more than 8 hours a day and/or weekend work is minimal but will vary depending on project deadlines and your responsibilities. 

·       Work Arrangement:  Onsite in the office/lab at 307 23^rd  St EXT, Suite 150, Pittsburgh, PA 15215 (Sharpsburg).

·       Physical Requirements:  While performing the duties of this job, the individual needs to have the ability to work in a laboratory setting for extended periods, manual dexterity for handling delicate laboratory instruments, standing or sitting for long durations, and lifting materials and equipment up to 25 pounds. Additionally, clear vision for observing experiments and data, safely handling hazardous chemicals with protective equipment, walking occasionally, using hands and fingers to operate tools or controls, and reaching with hands and arms are required.

·       Job Hazards : Hazards include potential animal materials (plasma, serum, blood, organs).  Employee may also be required to handle other hazardous substances of chemical or biologic origin after training.