Job Title – Sr . Research Associate , Immuno-oncology
Location – Foster City, CA - ONSITE
Duration – 12+ Months
Key Responsibilities
• Independently plan, execute, analyze, and interpret in vitro and in vivo immunological assays that support the initiation and/or advancement of drug candidate projects
• Proactively evaluate new technologies and develop new assays to accelerate early-stage discovery activities and/or enhance our understanding of disease mechanisms
• Manage multiple projects simultaneously and work cross-functionally with colleagues in the oncology, protein engineering, chemistry, translational medicine, biomarker and clinical groups
• Presents research findings and recommendations to senior staff and contribute to preparation of research reports, manuscripts, INDs, and patent filings
Knowledge, Experience and Skills
• Master's degree with 3+ years of experience, or Bachelor's degree with 5+ years of experience in immunology, immuno-oncology, cell biology, molecular biology, or biochemistry in industry or academia.
• Direct experience in research drug discovery and target identification/validation in oncology or immuno-oncology is highly desirable.
• Strong understanding of immune cell biology, including T cell and myeloid cells.
• Proficiency in primary T cell-based functional assays such as activation, proliferation and cytotoxicity.
• Experience in conducting and optimizing cell-based assays, as well as performing studies to assess immune responses in human and animal models (including whole blood, PBMCs, and various primary cell subsets).
• Hands-on experience in general molecular and cell biology methods, including mammalian cell culture, multi-color flow cytometry, western blot, ELISA/Luminex/MSD, and CRISPR technology.
• Attention to detail with excellent organizational and record keeping skills is a requirement.
• Excellent communication and interpersonal skills are required.