Job Title: Principal Scientist – Synthetic/Process Chemistry

Location: Hybrid in New Haven, CT (3-4 days per week on-site)

Client: Biotech Company in Oncology

About the Company:

A cutting-edge precision medicine company focused on oncology, with a promising early development pipeline targeting Oncology. The culture is collaborative, and this is a fantastic time to join a growing biotech firm with the potential for significant impact in cancer therapy development.

Role Overview:

The Principal Scientist – Associate Director will play a key leadership role within the synthetic/process chemistry team, focusing on the development and optimization of drug substances for small molecule oncology therapies. This position offers the opportunity to work in a fast-paced and innovative environment, contributing directly to advancing cancer treatments into clinical stages.

Responsibilities:

• Lead the design, development, and optimization of synthetic routes for small molecule drug candidates.
• Drive process development and scale-up efforts from lab to commercial scale.
• Collaborate with cross-functional teams, including medicinal chemistry, formulation, and manufacturing.
• Contribute to the preparation of regulatory filings and ensuring compliance with applicable quality standards.
• Provide leadership and mentorship to junior scientists, fostering a collaborative and dynamic team environment.

Required Qualifications:

• PhD in Chemistry or related field with 5-10 years of industry experience in small molecule synthesis and process development.
• Expertise in synthetic and process chemistry, with a proven track record in drug substance development.
• Experience within the biotech industry is highly preferred.
• Strong leadership and communication skills, with the ability to manage and guide a small team.
• Ability to work collaboratively across teams to drive project timelines and deliverables.