Responsibilities:
- The successful candidate will join multidisciplinary, highly collaborative discovery teams to invent novel medicines by applying optimized conjugation protocols, analytical techniques, and data analysis to synthesize drug candidates and intermediates.
- Successful candidates must have excellent interpersonal, collaboration, and communication skills in a team environment.
- Additionally, it is expected that the successful candidate will learn quickly through on-the-job training to become increasingly skilled and independent in reaction setup, route design and optimization.
Education Requirement:
- Minimum qualifications include a B.S./M.S/ PHD in chemistry, biochemistry, or related field, with industrial or academic experience.
Experience and Skills Required:
- Hands on experience with conjugation, purification and characterization of antibody drug conjugates, and experience using analytical techniques/instrumentation, including chromatographic techniques such as HIC (Hydrophobic Interaction Chromatography) and RP (Reverse Phase), SEC, SDS-PAGE, UV-Vis.
- Nice to have skills: Biologics analytic experience, purification techniques.
- Must have: Bio-conjugation experience, protein biochemistry and Chemistry background.
- Personality: Team player, Adheres to timeline, Communicative and collaborative.
Specific responsibilities will include:
- Perform bioconjugations of linker-payload combinations to antibodies with emphasis on in-house established methods
- Selection and application of appropriate purification techniques for biologics (i.e., SEC, hydrophobic interaction chromatography, ion exchange chromatography)
- Acquisition and interpretation of analytical data such as LC/MS.