Bio-conjugation Scientist

job
  • Integrated Resources, Inc ( IRI )
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Job Summary
Location
South San Francisco ,CA 94083
Job Type
Contract
Visa
Any Valid Visa
Salary
PayRate
Qualification
BCA
Experience
2Years - 10Years
Posted
20 Jan 2025
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Job Description

Responsibilities:

  • The successful candidate will join multidisciplinary, highly collaborative discovery teams to invent novel medicines by applying optimized conjugation protocols, analytical techniques, and data analysis to synthesize drug candidates and intermediates.
  • Successful candidates must have excellent interpersonal, collaboration, and communication skills in a team environment.
  • Additionally, it is expected that the successful candidate will learn quickly through on-the-job training to become increasingly skilled and independent in reaction setup, route design and optimization.


Education Requirement:

  • Minimum qualifications include a B.S./M.S/ PHD in chemistry, biochemistry, or related field, with industrial or academic experience.


Experience and Skills Required:

  • Hands on experience with conjugation, purification and characterization of antibody drug conjugates, and experience using analytical techniques/instrumentation, including chromatographic techniques such as HIC (Hydrophobic Interaction Chromatography) and RP (Reverse Phase), SEC, SDS-PAGE, UV-Vis.
  • Nice to have skills: Biologics analytic experience, purification techniques.
  • Must have: Bio-conjugation experience, protein biochemistry and Chemistry background.
  • Personality: Team player, Adheres to timeline, Communicative and collaborative.


Specific responsibilities will include:

  • Perform bioconjugations of linker-payload combinations to antibodies with emphasis on in-house established methods
  • Selection and application of appropriate purification techniques for biologics (i.e., SEC, hydrophobic interaction chromatography, ion exchange chromatography)
  • Acquisition and interpretation of analytical data such as LC/MS.

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