Source One is a consulting services company and we’re currently looking for the following individual to work as a consultant to our direct client, a global pharmaceutical company in San Diego, CA.

Job Title: Assay Development Scientist (Oligonucleotides Discovery Scientist) - Contract

Pay Rate: $52.26/hr (W-2)

Duration: 12 months with possible extension

Summary: Responsible for conducting research in assigned areas under direct supervision using established methodology. Plans and conducts moderately complex experiments and analyzes and interprets the results. Keeps accurate records of work undertaken.

Responsibilities:

• Support RNA assay development and chemistry by supporting RNA extraction, qPCR, immunoassays, and analytical methods to characterize oligonucleotides.

• Conduct and troubleshoot experiments, independently and in collaboration with colleagues, to characterize and screen siRNA oligonucleotides.

• Support siRNA characterization by through routine and consistent performance of 4 or more assays.

• Support lipid nanoparticle (LNP) development and characterization using dynamic light scattering (DLS), Encapsulation efficiencies (ribogreen fluorescence) and HPLC.

• Support routine tasks associated with siRNA solid phase supported synthesis and characterization using LC/MS.

• Collect and evaluate data; prepare reports, summaries, and presentations; maintain and update laboratory notebook and the laboratory information management system.

• Manage inventory of supplies, ordering reagents and consumables.

Requirements:

- Bachelor Degree in Science is required

- Must have exp in Laboratory

- Will support multiple groups including Chemistry group

- Must have Assay experience and knowledge

- Experience with QPCR

Experience in some of these areas would be ideal:

- Knowledge with therapies, RNAs

- RNA extractions

- LC/MS experience

- Reviewing concentration readings

- Lipid nanoparticle (LNP) exp

- Oligonucleotides experience

- Electronic Lab notebook exp

Additional Experience:

- Organizational skills

- Must have 5 years exp in Labs / technical exp

- Must have MS Office exp