Associate Director, Antibody-Drug Conjugates (ADC)

Location: Alameda, CA

Employment Type: Full-Time, On-Site

Reports To: Senior Director of R&D

Are you ready to lead groundbreaking advancements in oncology? We are seeking a highly motivated Associate Director, Antibody-Drug Conjugates (ADC) to drive the success of cutting-edge ADC and related development programs. This role is perfect for someone with a strong background in conjugation chemistry and linker-payload development who has demonstrated success in leading ADC programs from discovery through IND submission.

As a leader in this role, you will collaborate with internal teams and external partners to deliver innovative solutions that push the boundaries of ADC technology, with the ultimate goal of advancing life-saving cancer treatments.

Key Responsibilities

• Lead ADC pipeline programs, including bio-conjugation design, linker-payload optimization, conjugation process development, and preclinical study design.
• Oversee project timelines, budgets, and resources to align with corporate objectives and ensure timely milestone delivery.
• Prepare high-quality scientific documents, including peer-reviewed publications, study reports, and regulatory submissions (e.g., INDs).
• Collaborate with cross-functional teams, including clinical, regulatory, and manufacturing, to ensure seamless ADC development efforts.
• Partner with external CROs for ADC manufacturing, scale-up, and process development.
• Analyze experimental data and provide actionable insights to internal and external stakeholders.
• Contribute to the evaluation and integration of external assets into the ADC pipeline.
• Supervise and mentor junior scientists and research associates, fostering a culture of innovation and growth.

Required Qualifications

Education:

• Ph.D. in life sciences (oncology, immunology, chemistry, or related field) with a minimum of 8 years of industry experience, OR
• BS/MS with at least 12 years of industry experience in ADC development.

Experience:

• Proven expertise in linker/payload design and ADC development, including preclinical, pharmacokinetic, and pharmacodynamic studies.
• Hands-on experience with IND preparation and regulatory filings (e.g., IND, BLA).
• Strong knowledge of bioconjugation chemistry and analytical methods (e.g., LC-MS, HPLC, SEC).
• Familiarity with CMC processes, including manufacturing and scale-up for biologics.
• Exceptional scientific writing skills, with experience preparing regulatory documents and peer-reviewed publications.
• Excellent interpersonal and communication skills, with a history of successful collaboration in cross-functional teams.
• Proven ability to manage multiple projects simultaneously while meeting deadlines.

This is an exciting opportunity to contribute to transformative advancements in oncology and make a lasting impact. Join us in shaping the future of ADC technology and cancer treatment.