The Department of Neuroscience is seeking a bioanalytical scientist to join the MRL Discovery organization in West Point, PA.

• In this position, you will be responsible for developing mass spectrometry-based assays for use in preclinical drug development with a focus on neurodegenerative diseases with high unmet medical needs.

• Appointees will work within multidisciplinary teams focused on the discovery of Client drug targets and development of biomarkers for clinical translation supporting new therapeutics.

• Applicants should have expertise in development of quantitative mass spectrometry assays to support follow-on validation of discovery data for biomarker development.

If you are driven and open to learning in a team environment, come join our team.

Quals--

Job Title: Scientist III, Mass Spectrometry/Analyst, Discovery Neuroscience.

Education requirements

• PhD with industry or academic experience or Master's with at least 2-3 years of industry experience.

Experience/skills required:

• Hands-on experience in the development and technical validation of quantitative LC-MS/MS assays using MRM/PRM acquisition

• Experience in data analyses covering relative to absolute quantification

• Expertise in sample processing and prefractionation across cell, tissue and fluid specimens

• Experienced in using automated liquid handling platforms

• Experience working collaboratively within cross-functional teams

• Self-motivated and resourceful with a demonstrated ability to generate robust and reproducible data in a timely manner

• Well-developed oral and written communication skills

Desired Competencies (Preferred / not required):

• Hands-on experience performing unbiased, quantitative discovery analyses with high resolution LC-MS instrumentation (i.e. DDA, DIA approaches using label-free or TMT quantification)

• Proficiency in data processing with tools such as MetaboAnalyst, Skyline, MaxQuant, Proteome Discoverer, EncyclopeDIA or similar.

• Mass spectrometry-based targeted quantitative lipid analyses or discovery lipidomics.

Note:

• 100% lab based role.

Key skills to focus:-

• Hands on Mass spectrometry assays expertise needed.

• Developing quantitative assays using Mass spectrometry.

• Proficiency with tools such as MetaboAnalyst, Skyline, MaxQuant, Proteome Discoverer, EncyclopeDIA or similar.