About the Role

As a Senior Research Associate reporting into the Genomics Group, you will advance our genetic medicine technologies, enabling the discovery and development of new therapeutics. Working with a diverse team of cell biologists, protein and RNA engineers, computational scientists, molecular biologists, and translational biologists, you will:

• Conduct high-throughput processing of library prep samples for various sequencing methods, including Illumina NGS amplicon sequencing, ONT long read sequencing, methylation sequencing, enrichment-based sequencing, whole genome sequencing, and other innovative techniques.

• Extract genomic DNA from diverse cell types utilizing liquid handling robots to ensure precision and efficiency.

• Run QC samples through plate reader-based quantification, TapeStation, and qPCR

• Test, refine, and enhance existing SOPs to improve reliability and performance.

• Contribute to the development of novel methods aimed at unlocking previously unexplored regions of the genome.

• Serve as an expert in NGS sequencing and related workflows, always staying abreast of the latest advancements in the field.

Requirements

• A bachelor’s or master’s degree with a minimum of three years of experience owning NGS sequencing and the instrumentation and systems required to support it.

• A strong understanding of molecular biology fundamentals and best practices. • Familiarity with the setup and configuring of automation systems.

• A creative thinker with a track record of high-quality and attention to detail.

Preferred Qualifications

• Deep experience with Illumina NGS sequencing, including full library preparation and related workflows.

• Experience with Oxford Nanopore long read sequencing assays.

• Hands-on experience with liquid handling robots and expertise in developing and optimizing new protocols.

• Strong knowledge of DNA and RNA extraction methods across various sample types.

• Ability to conceptualize and implement workflows in a high-throughput environment, ensuring efficiency and scalability.

• Proficiency in designing, testing, and training others on new SOPs to enhance laboratory operations.

• Competence in data analysis using tools such as R, Python, Prism, and other relevant software